Press Release
☷NIST Develops Human Urine Standard for More Accurate Diagnosis of Kidney Disease
National Institute of Standards and Technology ( By Press Release office)
Dec 09,2023
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When you visit the doctor , they might ask you to give a urine sample for testing at a lab . This test can check for kidney disease and other conditions that affect kidney function . To accurately diagnose these conditions , doctors need precise measurements of certain compounds in urine . The National Institute of Standards and Technology ( NIST ) has developed a new standard reference material ( SRM ) called SRM 3666 , which contains carefully measured amounts of albumin and creatinine . This new standard will improve the accuracy and precision of clinical measurements for diagnosing kidney disease . It is important to have consistent and reliable test results in order to determine the risk of kidney disease accurately . The ratio of albumin to creatinine is typically used to assess kidney health . Albumin is a protein produced in the liver , while creatinine is a waste product filtered by the kidneys . High levels of these compounds in urine can indicate kidney dysfunction . Currently , there are standards for measuring creatinine , but there are none for albumin in human urine , leading to inconsistent measurements across different labs . The SRM developed by NIST provides accurate and precise measurements of albumin and creatinine in frozen human urine . It consists of four vials representing different levels of albumin in urine , ranging from normal to disease - indicating levels . This SRM will greatly assist in diagnosing kidney disease and support healthcare decisions . NIST has come out with a new standard reference material ( SRM ) that includes four vials containing different levels of albumin and creatinine found in urine . The levels cover a range from normal to disease - indicating levels . To create this material , Green worked with the clinical community to collect urine samples from patients with varying kidney function . The SRM comes with a data sheet providing accurate measurements for each vial , which laboratories can use for quality control when testing urine samples . By comparing their results to the data sheet , researchers can ensure their instruments are working correctly . This new SRM , focused on urine instead of serum , aims to improve clinical measurements and potentially impact diagnostic and treatment guidelines in the future . Interested organizations can purchase SRM 3666 ( Albumin and Creatinine in Frozen Human Urine ) from the NIST Store . For more information , contact NIST at the provided email or phone number .
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